Abstract: In grouting engineering, theoretical studies on the Yunnan red clay is immature yet. To adapt slurry grouting to different geologic conditions, the red clay properties could be improved and optimized with consideration of grouting requirements. In this study, a laboratory experiment was conducted and effects of different contents of cement and quick-setting agent on the performance of red clay cement slurry were examined and compared, using slurry viscosity in the range of 25-30 s, cement contents of 5, 10 and 15g /100 ml puree, and coagulant dosage levels of 1, 3 and 6g / 100 ml puree. The test results show that with the increasing cement content, slurry water rate increases and slurry stability is lowered but the effect of quick-setting admixture on slurry water rate is insignificant. In the experiment, slurry water rates for all the test sets were lower than 5% for slurry stability, and slurry gelation time with the agent dosage was adjusted in the range between a few minutes and a few seconds. The clay cement slurry gel time was the shortest of only 7 s when the agent content was 3 g/100 ml puree. The stone rate of slurry was increased with an increase in quick-setting admixture, and a swelling phenomenon occurred at the admixture of 6 g/100 ml puree. The more the cement content was, the more obvious the shrinkage of slurry stone body became. The permeability rate of the clay cement grout was decreased with an increase in cement admixture and it was insensitive to quick-setting admixture. An analysis on compressive strengths of the clay cement grout at the ages of 3, 7 and 28 days revealed that the grout stone strength grew slowly in earlier stage while fast in later stage, reaching the minimum strength of 0.13 MPa in three days and the maximum strength of 3.35 MPa in 28 days. And the compressive strengths of all the grout stone test sets were able to meet grouting requirements. The results above would provide a useful guide for practical grouting to achieve rapid preparation of slurry and slurry grouting in various geological conditions and effectively improve control on grouting procedure, reducing abandoned cement slurry and grouting cost.